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Mouse

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New Products

Rec M TGF-beta 3

Recombinant Mouse Transforming Growth Factor beta 3 (TGF-beta 3 Mouse) Synonyms: TGF-beta 3 Description: The TGFs proteins are multifunctional peptides that regulate growth and differentiation in a variety of cells. Data suggests that individual TGF-β isoforms (TGF-β1, β2 and β3) have overlapping, yet distinct biological actions and target cell specificities, both in developing and adult tissues. TGF-β3 is a new isoform that is presumed to play an important role in wound repair and sc...

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Rec M Activin A

Recombinant Mouse Activin A (Activin A Mouse) Synonyms: Inhibin beta-1, FRP, FSH-releasing protein Description: Activin A is a member of the TGF-beta family of proteins produced by many cell types throughout development. Activins interact with Type I and Type II serine/threonine kinases to signal to SMAD proteins to regulate a variety of functions, including cell proliferation, differentiation, wound healing, apoptosis, metabolism, etc. Activin A is a homodimer of two beta A chains and is ...

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Rec M Follistatin

Recombinant Mouse Follistatin Synonym: FSH-suppressing protein (FSP), FS, activin-binding protein. Description: Follistatin is an autocrine acting protein that is expressed by many tissues, but at noteably higher levels in the ovary and skin. Follistatin functions to negatively regulate the signaling of a wide variety of TGF-beta family members (activin, BMPs, myostatin, GDF-11 and TGF-beta1). Mechanistically, follistatin works as an antagonist by complexing with TGF-beta family members to...

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Rec M IL-12

Recombinant Mouse Interleukin-12 (IL-12 Mouse) Synonym: NKSF, CLMF Description: Interleukin-12 is an important mediator of cellular-immunity produced by dendritic cells, macrophages and B cells when stimulated with antigen. IL-12 is involved in differentiating precursor helper T cells to Th1 and/or Th2 subtypes and promotes the production of IFN gamma and TNF alpha. Mouse IL-12 is active on human and mouse cells. Recombinant mouse IL-12 is a glycosylated, disulfide-linked heterodimer. It i...

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